Patient: I dont know if my question is beyond the expertise of some of the Dr on this board. If not I apologize. I was told yesterday that I am a carrier of the Alpha 1 tris gene. My phenotype is pi mz. I had the test due to elevated liver functions without any cause. numerous MRI ultrasounds and dozens of whacky blood tests. My Dr who is a pulmonary specialist and gp sent me to a liver specialist in mt sinai hospital nyc. Where I was tested. My gp Dr states that being a carrier is of no real risk to me, just that I should not smoke. He said that my body does produce enough AAT My range is 88 mg ref 82 to 169. I read that being a carrier can increase my chances of getting lung disease. I had the flu last week and still have a cough for about two weeks .My Dr says it can take sometime and the cough has nothing to due with my results. The liver specialist said in the report that he has seen in some cases increased fibosis in setting like mine. would the Mri and ultrsound showed this. My alt 93
Your gp is correct, as long as you don’t smoke your chances of developing COPD is not increased. Dr Seersholm wrote a 2004 article that addressed this specific topic. His research showed that people with pimz did not have an increase incidence of lung disease as long as they did not smoke. The reason is because a pimz still has, at a minimum 60% AAT. This is enough to stave of lung disease in someone with A1AT def. The cough, is a response that can last for weeks to even a month or longer. The reason is not the lungs (in this case) but the bronchi. The cough is often the very last thing to leave or get better. This is seen in almost all cases of any respiratory issue. Since your numbers are good I would not worry that all of a sudden you developed a lung disease. As for the liver, the MRI or ultrasound would have shown fibrosis of the liver. Your clotting factors would be out of whack. Your protein would be low. It doesn’t appear that this is the case. I would have to agree with your gp on the lung issue and would say that your hepatologist (liver doc) may have seen some cases of worsening, but I guarantee you this was the Continue reading I dont know if my question is beyond the expertise of some of the Dr on this board.
Patient: I am 49 years old and my period stopped 3 months ago. I have been experiencing a burning pain on the left side. It also feels like it is itching and I have pain along my low back. What could this be?
Already Tried: Pelvic exam one in July. It was normal.
Doctor: Please let me know if this is deep pelvic discomfort or superficial–as if your skin is burning or itching. Any history of heavy periods or this type of pain in the past? Any history of cancer in you or your family?
Patient: The discomfort is deep and sharp and the burning and itching sensation is coming from within. I have never had heavy periods. The last period I had was in August. I have not had cancer. My mom had breast cancer. I’ve had 3 separate experiences with cysts but the last time was in the mid-90’s.
Doctor: This certainly is concerning for an ovarian cyst. However, pelvic discomfort is sometimes related to your bowel function. If you have not had diarrhea or constipation, I recommend visiting your ob/gyn. Your mother having breast cancer may put you at higher risk for developing ovarian cancer if related to a genetic disorder (BRCA), however, this is usually more certain if you’ve had at least two close Continue reading I am 49 years old and my period stopped 3 months ago.
Patient: Question in regards to the development of cancer. Is it known how long it takes for a cancer to develop?. I had a abdominal ultrasound and abdominal MRI about (3) months ago the MRI showed a very small non enhancing liver cyst about 2 mm in size, the radiologist called the test unremarkable. I also have a spleen hemangioma that has been unchanged for about three years about 1 1/2 cm in size. Every 12 to 18 months I go for a full abdominal MRI for the spleen and I also get a endoscopy every 12 to 18 months for my reflux (NO BARRETTS). I had a colonscopy last month no polyps. My Gastro DR seems to give me alot of testing. When I tell other people that I get some many tests they say how come???. Is a MRI every year excessive
or would this help me catch any problems very early??? Or does it not matter? can a cancer grow out of no where to a stage 3 or 4 in less than a year. everything I read says cancer takes years to develope before symptoms appear. I am 40 male
Already Tried: mri ultrasounds bloodwork colonscopy
Doctor: I agree with what you are saying. I think that an MRI every year excessive. Even a colonoscopy which is done to screen for cancer of the colon is done every ten years after the age of 50. An MRI of the abdomen IS NOT a recommended test to screen for Continue reading Question in regards to the develoment of cancer. Is it known